Hello, Kieran Thompson! This is a great work that you have done today and I do not see anything that is wrong with this piece (I copied and pasted this whole entire work to Microsoft Word Processor and there were no actual errors in this very short piece) except that fact of:

She fixed herself and leaned onto my arm and I felt so strong and so  my arm and I felt so strong and so weak

What is the deal with the "She fixed herself and leaned onto my arm and I felt so strong and so weak?" That is a contradiction. How can you feel strongness and weakness at the same time? To clear up this problem, you should say a little something like She fixed herself and leaned onto my arm. She felt so strong and I felt so weak. I do not know if the "She felt so strong:" part will work a bit, but the sentences that I did in bold faced words at least made more sense, right? I believe that you have much potential into this work and with that suggestion that I just gave you, I think that your story could be among the very highest rated works on this site! I look forward to reading more of your works! Take care!

 Wow...gritty piece. I get an impression of a love/hate relationship between the two. Perhaps their relationship was a reflection of their love/hate relationship with drugs. Interesting. You've created some intriguing characters here. I hope you will continue to develop this into an arresting piece of prose.

The problems I have are purely technical and quite picky, so do as you wish. If you hope to have this published though, you might want to be exceptionally picky - it's a jungle out there. So here goes:

"smoke filled squalid" should be smoke-filled, squalid. The word "vaguest" dilutes your simile - glass marbles would just reflect light, the word "vague" is confusing in this context. Take out the comma between floor and leaned and add "and". This makes the sentence more clear as to who or what leaned against the couch.

 Demons were pouring in and out of the door to this shooting gallery of a home with the cigarette smoke.

This sentence could be more powerful. Take out "were" (passive) and change it to active - Demons poured ... the sentence has four prepositional phrases and you've already established that it was filled with smoke and by saying in and out of the door, you imply that she left the door open and that demons need a door to enter and exit.

Demons poured in and out of the shooting gallery we called home.

Maybe that's just personal preference, but a clean clear image is preferable to superfluous redundancy- no offense. You already stated that she sat next to you. Maybe you should say she looked at you or leave that out altogether - it doesn't add anything. When you use dialogue, you need to set it off like this:

She wordlessly lifted my arm up with her hand like a priest placing communion into the mouth.

 

“I’ll see you at the bottom,” she whispered and fired a skeletal grin in my direction…her eyes were like luminescent sickly yellow high beams as she slid the thin spear into my forearm.

 The syntax gets a bit mixed up and could be sharper by removing all unnecessary verbiage. Try something like this:

She wordlessly lifted my arm like a priest placing communion into the mouth. 

 

“I’ll see you at the bottom,” she whispered, eyes like luminescent sickly yellow high beams, firing  that skeletal grin into me as she slid the thin spear into my forearm.

 I'm just going to put the rest of the fine-tuning and my comments in parenthesis.

Her gaze never broke as roses blossomed through the diabetic syringe. (awsome line) She sighed orgasmic(ly) like she was sucking the vapors of it out of my breath, watching as the smack hit my system and I sunk down into warm, itchy oblivion.

 

I hunched over and absently stared at the tattered photocopy of our marriage license attached with yellowed scotch tape to the coffee table…the joke was that in case we got pulled over sleeping together, by God, we could provide license and registration for ourselves. It was a one-time joke but for some reason we never took it off. It just seemed appropriate for it to stay where it was.

 I'm not sure why you were driving around with a coffee table. Maybe there's something  missing?

She fixed herself and leaned onto my arm. I felt so strong and so weak. It was a honeymoon in hell. We stared at our feet for what seemed an eternity as the blood gently exiting the tiny needle mark in Ezra’s arm formed a droplet that streaked a crimson line over her pale skin. To some it may have seemed like we had long since forgotten the vows we’d made some five years ago. They were gravely mistaken; we were doing just that. Till death do us part and we goddamn meant it. If you’re going to destroy yourself, might as well have a partner to help.

 This story is indescribable.  You've done an excellent job bringing so much reality to a depressing situation.  Your story is very powerful, even though I heard myself groaning through a lot of it, because it was so real.  Your descriptions are very good.  I could picture every scene that you wrote about.

Their relationship is interesting.  LIke someone else said, sort of a love/hate relationship.  When a person is that deep into the grip of drugs, they lose their presepective of reality, not to mention their feelings.  So, if the two had loved one another at some time, they certainly didn't once they began the drug use.  The part that really creeped me out was when she said:

I'll see you at the bottom.

That was really scary, and showed the reader how fall they've fallen. Also, I thought I caught a long run on sentence.  Let's see if I can find it. Oh, I see it now.  I'm not sure if it's a run on or not, but it's the sentence where you're talking about the marriage certificate.  You do use three periods, but I'm not sure about that either.  You may want to check it out, just in case.

 

 

The ending was depressing.  They'd gone as far down as they coudl go, but it ends very dramatically too.  It fits the mood and plot of the story.  I don't think any other ending would fit, in this case.

 

 

Well, there it is.  Hope I helped a little.  At least you got my reactions, and that's usually the way my crits are, unless there are lot of grammatical mistakes.   Thanks for sharing this story, and I wish you luck on the rewrite.

 

Cathy